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A well-produced musical number that's orchestrated well makes it 10 times funnier, when it actually sounds really good.
Absolutely, we were influenced by The Simpsons. We'd be stupid not to be. They put that out there, and we took a cue from that.
'American Dad' is, by its nature, much more political.
At this point, there are a lot of high-profile actors who are fans of the show, and it's easier for us to bring those people on than it used ... (more Seth MacFarlane quotes)
He did some work on Cartoon Network series, Johnny Bravo.
His old high school headmaster publicly criticised him for his "low brand of humour."
Seth: (as Stewie, on Countdown With Keith Olbermann on MSNBC, mocking Bill O'Reilly) :
Oh wait Bill. Stay right where you are. I want to soil you!
He has said that his voices of Stan Smith on American Dad! and Stewie on Family Guy are his... (more Seth MacFarlane trivia)
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